Synthetic applications of Laccase and its Catalytic Potentials

Abstract

Laccases benzenediol: oxygen oxidoreductase (EC1.10.3.2), multicopper containing oxidoreductase enzymes, are able to catalyze the oxidation of various low-molecular weight compounds, specifically, phenols and anilines, while concomitantly reducing molecular oxygen to water. Because of their high stability, selectivity for phenolic substructures, and mild reaction conditions, laccases are attractive for fine chemical synthesis. This manuscript provides a discussion of the recent applications of this interesting enzyme in synthetic chemistry, including laccase and laccase-mediator catalyzed reactions. There for fungal laccases are consider as a perfect green catalysts is a prominent biotechnological applications. Thus laccases find potential applications in bleaching of paper pulp, biofuel cells and organic synthesis. They can perform transformations from the oxidation of functional group to the hetero nuclear coupling product of new antibiotics derivative.