Pharmacotherapy Safety Assessment in Patients with Rheumatoid Arthritis Treated in a Regional Health Bahia
Abstract
Rheumatoid arthritis is an autoimmune disease characterized by affect the joints causing chronic inflammation and premature death in the same. The present study is descriptive / observational and analytical, following a cross-sectional study of the association between a medical conditions (rheumatoid arthritis) of patients treated with synthetic and biological. The invitation to participate in the study was done in the following ways: in person, that is, by approaching the individual at the Regional Health Center of the Southwest Regional Health Center and by telephone, using a list of patients receiving the medicines for treatment of RA in the Specialized Component of Pharmaceutical Care in the NRS-S pharmacy. After the arrival of the individuals, they were referred to a particular room, where explanations were made of every procedure that would be performed and guidelines necessary for their participation in the research. The guests who agreed to participate signed the Free and Informed Consent Form.it was observed that of the 54 patients, only (5.7%) presented alteration in the OGT exam and (7.5%) in the CGT. Regarding the GGT analysis, 52 patients were used because of a loss that occurred during the analytical process, identifying the presence of lesions in 10 individuals, representing (19.2%) of this sample. In summary, (1.9%) of the studied population had creatinine and urea exams above the reference value, that is, characterizing a probable nephrotoxicity. In relation to the hematological cells, it was reported that (9.3%) of the population obtained erythrocytes below the reference value, as well as a decrease in leukocytes in (5.6%) of the population. And finally, the platelets were within the reference value. According to data obtained in the study, it was possible to identify, in a general way, changes in laboratory tests, independent of the treatments used. Thus, the presence of these reactions’ compromises patient safety, providing health risk factors for individuals.
