Metabolic Syndrome in Quilombola Populations Environmentally Exposed to Organophosphate Pesticides in the State of Pará- Brazil

Abstract

The quilombola community Médio Itacuruçá in the municipality of Abaetetuba is in permanent contact with Organophosphate pesticides. Knowledge about this environmental exposure and the Metabolic Syndrome (MS) can be especially useful for understanding its impact on human health. Materials and methods: descriptive, cross-sectional study. Sample of 115 individuals, over 18 years old, both genders. Erythrocyte Acetylcholinesterase (AChE) values between 2.6-4.1 IU/mL and butyrylcholinesterase (BChE) values between 1.5-3.5 IU/mL were considered within the normal range. The diagnosis of Metabolic Syndrome (MS) was established according to the Joint Interim Statement protocol. Results and Conclusion: 33% of the quilombola population had MS. In the group with MS, the average value of BChE was 3.60 IU/mL, and in the control group, 3.94 IU/mL. The Mann-Whitnney U test was also performed to define the p-value, getting a result of 0.38. The AChE values were 6.92 IU/mL in the research group and 6.94 IU/mL in the control group, obtaining p-value by the Mann-Whitnney U test of 0.974. Thus, there was a low association between AChE, BChE and MS.