Synthesis and Characterization of Bioactive Glass - In Vitro Studies

Abstract

Melt quench experimental method was used to prepare a new B2O3 based bioactive glasses with low lithium bromide and low lithium fluoride content. The aim of this work is to investigate the bioactivity nature of prepared glass samples with composition Na2O-LiBr-SrO-CdO-B2O3-P2O5 and Na2O-LiF-SrO-CdO-B2O3-P2O5.The melt derived glass ceramics were characterized by using X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM) and Energy Dispersive Spectroscopy (EDS). For In vitro studies, the bone bonding ability is evaluated by examining the formation of hydroxyl apatite layer (HCA) on its surface when treated in Simulated Body Fluid (SBF) for few days. SEM and EDS analysis were used for surface morphology of the glass ceramics as well as to detect the presence of crystalline phase hydroxyl carbonate apatite (HCA) formation onto the surface of glass ceramics. SEM and EDS confirms the in vitro bioactivity of glass ceramics.