Investigation of Inhibitory Potential of Monkey Cola (Cola Milleni) against some Microorganisms

Abstract

Microorganisms are used in processing bulky, perishable and inedible raw materials into safe, shelf- stable and palatable foods. The microbial activity of aqueous and ethanol extracts of pods and seeds of Monkey cola was evaluated for potential antimicrobial activity against important bacterial and fungal strains common to plants and animals. The antibacterial and antifungal activities of extracts from the seeds and pods of Monkey cola were tested against five bacterial strains — Escherichia coli, Erwinia carotovora, Xanthomonasaxonopodis, Staphylococcus aureus, and Pseudomonas solanicearium, and four fungal strain; Colletotrichum gloesporioides, Phytophthora megacarrier, Colletotrichum acutatum and. Fusurium oxysporium using standard methods. The zone of inhibition of the extracts were compared with standards of amoxicillin ciprofloxacin, for antibacterial and kocide for antifungal activity. The results showed remarkable inhibition (13-33mm) of the bacterial growth against the tested organisms. The antifungal activity of seed ethanoic extract result showed maximum mycelial growth of 100 percent against tested fungal organisms. Hence, the plant is recommended as bioactive natural product that may serve as leads in the development of new pharmaceuticals products against microorganisms in both plants and animals.