Adverse effects Associated with Third-Booster COVID-19 Vaccine (Heterologous Vaccines by Sinovac- Moderna) among Health Care Workers

Authors

  • Nur Idayanti
  • Dwi Sutiningsih
  • Mochamad Hadi M
  • Imam Abrori

Keywords:

SARS-CoV-2, adverse effects, heterologous vaccine.

Abstract

The mRNA 1273 vaccine by Moderna©has recorded to be94.1% effective against laboratory-confirmed Covid-19 infection. Health care workers in Indonesia are receiving third-booster vaccine by Moderna after the two doses of virus-inactivated vaccine. Further evaluation of Covid-19 mRNA vaccine post-injection effects on health care workers is necessary. This present study asssessed the post-immunization adverse events tohealth care workersin the Port Health Office of Semarang.This was a retrospective, cross-sectional, observational study aimed to the HCWs, both staff and non-staff, of the Port Health Office of Semarang.We identified and analyzed the adverse effects on 132 workers who had been receiving third-mRNA booster vaccine by Moderna. About 37.8% (50 out of 132)respondents experienced adverse events after receiving third-booster vaccine by Moderna. Among them, female workers (62%) had more incidents compared to males (38%). the most common symptoms were localized painon injected arm (100%), fatigue (44%), fever (42%), myalgia (38%), and chills (30%). Other symptoms like night sleep issue, diarrhea, nausea, an headacheswere also reported.The mRNA 1273 vaccine by Moderna©injection as booster provides several severe but not life-threatening symptoms, most of the emerging cases are fatigue and fever and and possibly correlated with gender.

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Published

2022-01-03

How to Cite

Idayanti, N., Sutiningsih, D., Hadi M, M., & Abrori, I. (2022). Adverse effects Associated with Third-Booster COVID-19 Vaccine (Heterologous Vaccines by Sinovac- Moderna) among Health Care Workers. International Journal of English Literature and Social Sciences (IJELS), 6(6). https://journal-repository.com/index.php/ijels/article/view/4526