Study of Spectrum of Adrenal Changes Autopsied at J.L.N. Hospital Ajmer

Abstract

Background- Adrenal glands are the least studied organ. Aim and Objectives- 1. To analyse gross and microscopic morphology of adrenals in posmortem cases and their correlation if any with the cause of death. 2. To compare the adrenal changes in various layers along with sudden natural death. 3. To compare the adrenal changes in person dying due to debilitated condition like TB, CANCER. 4. To compare the adrenal changes in chronic hypertensive and end stage renal disease. 5. Death in corona pandemic due to COVID-19. 6. Death due to poisoning. Material and Methods- This observational cross section study will be carried out in the department of forensic medicine and toxicology on 100 cases in JLN Medical college and attached hospitals with cooperation from the department of pathology after obtaining due permission from the institutional ethical committee. Conclusion- Adrenal lesion can present in various forms at autopsy. Non-neoplastic Lesions should be given equal importance as neoplastic. An enlarged adrenal does not always indicate malignancy. There are many clinical conditions in which adrenals are affected as secondary phenomenon. Gross and histo-morphological examination of the tissue can diagnose the adrenal lesions with great accuracy and is beneficial for patient’s further survival, in setups where facilities to perform adrenal biopsies are available. Adrenals should be investigated as a part of routine autopsy procedure in all post-mortem cases.