An observational descriptive study of pattern of pathological changes in liver in context of medico-legal autopsy done at J. L.N. Hospital, Ajmer

Abstract

Background- Autopsy finding in liver with pathological changes are studied. Aim and Objectives- To correlate histopathological findings in the liver with gross examination in routine medicolegal practice of autopsy. To find out the type of liver diseases in relation to age and sex of the studied autopsy cases from the local population. To assess and compare histopathology of liver among accidental deaths, sudden natural deaths and deaths due to poisonings. To compare results of this study with other studies. Suggestion of authenticity of diagnosis from the histopathology findings of liver. Material and Methods- This observational cross section study will be carried out in the department of forensic medicine and toxicology on 100 cases in JLN Medical college and attached hospitals with cooperation from the department of pathology after obtaining due permission from the institutional ethical committee. Conclusion- hepatic lesion can present in various forms at autopsy. Non-neoplastic Lesions should be given equal importance as neoplastic. An enlarged liver does not always indicate malignancy. There are many clinical conditions in which liver are affected as secondary phenomenon. Gross and histo-morphological examination of the tissue can diagnose the liver lesions with great accuracy and is beneficial for patient’s further survival, in setups where facilities to perform liver biopsies are available. Liver should be investigated as a part of routine autopsy procedure in all post-mortem cases.